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Elevated intracellular Ca 2+ inhibits flippase and activates scramblase, moving PS to the erythrocyte surface [108, 109]

Wide complex tachycardia should be presumed to be ventricular tachycardia when the diagnosis is unclearparticularly if it occurs in the presence of structural heart diseaseand requires further evaluation

178 Furthermore, molecular biophysics studies suggest that hormonal fluctuations can influence the expression and activity of integrins and other cell-adhesion molecules in fibroblasts, the cells responsible for collagen production and maintenance